Delayed Intubation Rarely Needed for Opioid Overdose in ED

TOPLINE:

Patients presenting to the emergency department (ED) with presumed opioid overdoses now not regularly wished delayed intubation, suggesting that these sufferers might fair be safely managed out of doors of an intensive care unit after 4 hours of ED monitoring.

METHODOLOGY:

• This secondary diagnosis of the Fentalog Stare incorporated 1591 sufferers with suspected acute opioid overdose who introduced to EDs within the United States.
• Suspected opioid overdose change into once identified via opioid toxicity diagnoses, naloxone administration, or self-reported opioid use resulting within the ED seek recommendation from.
• The main final result change into once the percentage of sufferers who got delayed intubation following suspected opioid overdose, with delayed intubation outlined as endotracheal intubation occurring higher than 4 hours after arrival at a health center.

TAKEAWAY:

• Total, most effective 9 sufferers required delayed intubation.
• Eight of the 9 sufferers who required delayed intubation had indications for intubation rather than hypoventilation-prompted respiratory failure.
• Naloxone change into once administered to seven sufferers with delayed intubation, with four sufferers receiving three or more doses.
• Most efficient one patient who required delayed intubation due to the hypoventilation got 5 doses of naloxone (a whole of 6.4 mg).

IN PRACTICE:

“In conclusion, this peep stumbled on an especially low rate of sufferers requiring intubation for respiratory failure after 4 hours of monitoring, equipped they to birth with introduced with presumed opioid overdose. The low rate of delayed intervention (delayed intubation) means that opioid overdose disposition can catch to continue to be in response to comprehensive clinical assessments and ongoing reassessments, emphasizing the efficient use of resources,” the authors wrote.

SOURCE:

This peep change into once led by Daniel J. McCabe, MD, Department of Emergency Treatment, University of Iowa Carver College of Treatment, Iowa Metropolis, Iowa. It change into once revealed on-line on March 04, 2025, in Annals of Emergency Treatment.

LIMITATIONS:

Even though files were aloof from several sites, they weren’t nationally representative, potentially limiting generalizability. The little desire of sufferers with delayed intubation restricted the statistical analyses on this peep. The exclusion of a serious share of sufferers from the Fentalog Stare can catch introduced bias to all subsequent secondary analyses.

DISCLOSURES:

This peep got pork up from the Nationwide Institute on Drug Abuse of the Nationwide Institutes of Successfully being. The authors reported having no conflicts of interest.

This text change into once created the utilization of several editorial tools, including AI, as phase of the procedure. Human editors reviewed this drawl material before newsletter.