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These Factors Up Retina Detachment Risk by 16x in Marfan

 These Factors Up Retina Detachment Risk by 16x in Marfan


In children with Marfan syndrome who undergo lens removal, the anguish for retinal detachment increases 16-fold when capsular residue is most up-to-date and by 30% with lift in axial length.


  • Researchers assessed the anguish factors for retinal detachment in 85 children (158 eyes; imply age at surgical map, 5.3 years; 58% boys) with Marfan syndrome who had surgical map to get rid of a lens between January 2010 and January 2020.
  • All patients underwent a complete ophthalmologic examination sooner than surgical map and at each and each apply-up which incorporated simplest-corrected visual acuity, evaluation of anterior and posterior segments, and intraocular stress. Axial length and corneal curvature additionally had been evaluated sooner than surgical map.
  • The researchers composed recordsdata on capsular residue after surgical map, implantation of intraocular lenses, and assortment of surgical procedures performed.
  • The major final result used to be the incidence of a retinal detachment all over the apply-up interval after surgical map.


  • At a median apply-up of 11.5 years, 24 patients (35 eyes) developed retinal detachment, with loads of tears seen in the majority (65%) of the eyes.
  • Incomplete removal of the capsular safe increased the anguish for retinal detachment practically 17-fold (odds ratio, 16.8, P = .01).
  • The rise in axial length raised the anguish by 30% (P = .03).
  • The cumulative anguish for retinal detachment after lens removal increased from 8% at 5 years to 15% at 10 years.


“When lens subluxation is main, capsular desires to be thoroughly and entirely eradicated. Apply-up desires to be started early and persisted for a protracted duration after surgical map, and physicians desires to be critically cautious in patients with increased axial length and with a history of retinal detachment,” the authors wrote.


Youssef Abdelmassih, MD, from the Pediatric Ophthalmology Department on the Rothschild Basis Clinic, in Paris, France, led the scrutinize, which used to be published online on Might perchance 29, 2024, in the American Journal of Ophthalmology.


The scrutinize used to be retrospective in form, with many children misplaced to apply-up. A pair of surgeons performed lens removal with totally different lens kinds and implantation ways, which could well earn affected the construction of retinal detachment. The scrutinize used to be performed at a tertiary referral facility with a pediatric vitreoretinal division, that would earn ended in an overestimation of the incidence of retinal detachment as many patients had been referred for the management of retinal detachment.


This scrutinize did no longer receive any funding. The authors declared no conflicts of interest.

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