Stiff Arteries Raise Glaucoma Risk?

TOPLINE:

Arterial stiffness will increase the chance for constructing glaucoma, a brand new see chanced on.

METHODOLOGY:

• To see the link between arterial stiffness and glaucoma, the researchers evaluated 4713 folk (indicate age, 66 years; 58% males) without the leer situation at baseline between April 2011 and November 2012.
• They assessed arterial stiffness by measuring aortic pulse wave tempo, estimated carotid-femoral pulse wave tempo, and aortic pulse tension.
• The predominant final consequence was once incident glaucoma, recognized from prescriptions for leer drops or health heart records.

TAKEAWAY:

• Total, 301 folk within the see developed glaucoma over a median follow-up duration of 10.5 years.
• For every not recent deviation lengthen in aortic pulse wave tempo, individuals had a 32% greater risk for constructing glaucoma (standardized hazard ratio [sHR], 1.32; 95% CI, 1.10-1.60), while estimated carotid-femoral pulse wave tempo was once associated with a 37% greater risk (sHR, 1.37; 95% CI, 1.11-1.70).
• Incident glaucoma elevated throughout all quartiles of arterial stiffness, with the finest risk observed within the fourth quartile for aortic pulse wave tempo (HR, 2.41; 95% CI, 1.36-4.26), estimated carotid-femoral pulse wave tempo (HR, 2.29; 95% CI, 1.27-4.13), and aortic pulse tension (HR, 1.76; 95% CI, 1.10-2.82).
• The cumulative incidence of glaucoma rose with will increase in arterial stiffness. This pattern was once statistically vital for each and every aortic and estimated pulse wave tempo (P < .0001) and aortic pulse tension (P = .02).

IN PRACTICE:

“Arterial stiffness…which is able to be without trouble and precisely measured, can also very successfully be used as a tool in clinical educate [as part of routine blood pressure measurement] to attend establish folk in menace of glaucoma and as a therapeutic target to terminate glaucoma progression,” the authors wrote.

SOURCE:

This see was once led by Angela L. Beros, MPH, of the College of Population Health on the University of Auckland, Auckland, New Zealand, and published online on Would possibly well well 14, 2024, within the American Journal of Ophthalmology.

LIMITATIONS:

The cohort see did not clinically assess for glaucoma, doubtlessly main to the inclusion of folk with the situation. No longer all individuals with incident glaucoma, particularly these unaware of their diagnosis, can also were recognized. Intraocular tension and central corneal thickness, which could well be identical old risk factors for glaucoma, weren’t integrated within the multivariate diagnosis.

DISCLOSURES:

The see did not receive any funding. The authors declared no conflicts of ardour.