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One Man’s Journey With Chronic Eczema

 One Man’s Journey With Chronic Eczema

Eric Gray’s whisk with eczema—a two-year saga—started innocently ample. On vacation in Florida alongside with his household, he observed a faint red squawk on his hip. Whereas the patch became itchy and barely of infected, he didn’t judge grand of it. However the irritation didn’t dash away.

Diagnosing His Condition

Coincidentally, his companion became dealing with shingles at the time on the particular identical squawk on her body, so Gray figured he could perchance well wish the identical viral infection. He visited his physician and became prescribed medication for shingles. However as the itchy rash started spreading to other areas of his body—his decrease legs, relief, arms, and fingers—it grew to turn out to be obvious that he didn’t own the particular diagnosis.

And ruling out shingles didn’t discover him any nearer to an answer. One dermatologist thought the rashes own been warts and wished to burn them off. But one more thought he could perchance well wish a hazelnut hypersensitive reaction. “I completed without hazelnuts as directed, nonetheless I kept itching your complete time without a relief,” he remembers. Sooner or later, Gray became diagnosed with atopic dermatitis, the commonest own of eczema and a persistent situation that causes the pores and skin to turn out to be infected, dry, and itchy.

Discovering Medications

Placing a fame to Gray’s situation became only half the battle; figuring out how one can deal alongside with his eczema proved to be true as nerve-racking as diagnosing it had been. “I tried so many creams,” Gray says. “I level-headed own a container fleshy of potentially 10 different tubes. Some of them helped temporarily, nonetheless none equipped the relief I became trying for. I couldn’t sleep at evening attributable to the constant itching, and it started to concern me at work. It became changing into very now not easy.”

His indicators afflicted him finally of his day to day life, from his profession as an electrician to hobbies luxuriate in golf and going to the gym. They grew to turn out to be so burdensome that he had to sleep with petroleum jelly and rubber gloves on his fingers to aid himself from scratching finally of the evening. He didn’t dash away the residence without pores and skin cream or lotion to have a study hourly to his infected areas. “I became itching so grand,” Gray says. “My true hand, down into my thumb and first two fingers, became cracked and itching constantly.”

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Subsidized by Incyte

Discovering Relief

After months of trial and error, Gray’s physician asked if he’d be willing to confirm out a original prescription topical medication known as OPZELURA® (ruxolitinib) cream 1.5%, a non-steroidal cream that’s FDA-popular for the brief-term and non-continuous medication of delicate to moderate eczema in distinct of us damaged-down 12 and over whose illness is now not neatly managed with topical prescription therapies or when these therapies are now not instantaneous. The usage of OPZELURA alongside with therapeutic biologics, other JAK inhibitors, or solid immunosuppressants fair like azathioprine or cyclosporine is now not instantaneous.

OPZELURA is now not for all and sundry. Look below for IMPORTANT SAFETY INFORMATION including boxed Warning for Important Infections, Elevated Risk of Death, Lymphoma and other Cancers, Foremost Cardiovascular Events and Blood Clots.

After the usage of OPZELURA, Gray stumbled on that inside of a couple of days the itching became long previous, and in a couple of weeks his pores and skin started to obvious. “I couldn’t imagine it,” Gray says. (Please clarify, person results could perchance well merely range.)

Gray has been the usage of OPZELURA twice day-to-day as wished for over a year now. Upkeep medication with the medication is easy, requiring only a skinny layer of the medication twice a day*. Having a glimpse relief on his whisk, Gray emphasizes that the foremost to overcoming his struggles with eczema became staying diligent and taking part alongside with his dermatologist to search out a medication option that became most attention-grabbing for him.

“I kept trying things and at last stumbled on one thing that labored. It’s the truth is helped to alleviate my indicators,” he says. “I succor others experiencing pores and skin points now to not renounce. Enact your overview and depend to your physician about OPZELURA. Discovering the true medication for yourself makes your complete incompatibility.”

Eric is a paid participant in Inycte’s “Moments of Clarity” program, highlighting the first price tales of of us living with delicate to moderate eczema and their whisk to discovering relief from their indicators. To listen to more from Eric and others who stumbled on relief with OPZELURA, focus on with MyMomentsofClarity.com.

*End the usage of when indicators and indicators (e.g., itch, rash, and redness) of atopic dermatitis discover to the bottom of. If indicators and indicators produce now not enhance inside of eight weeks, sufferers wishes to be re-examined by their healthcare provider.

IMPORTANT SAFETY INFORMATION

OPZELURA is to be used on the pores and skin only. Enact now not employ OPZELURA on your eyes, mouth, or vagina.

OPZELURA could perchance well merely trigger severe aspect results, including:

Important Infections: OPZELURA contains ruxolitinib. Ruxolitinib belongs to a category of medicines known as Janus kinase (JAK) inhibitors. JAK inhibitors are medicines which own an impact to your immune machine. JAK inhibitors can decrease the flexibility of your immune machine to fight infections. Some of us own had severe infections while taking JAK inhibitors by mouth, including tuberculosis (TB), and infections caused by bacteria, fungi, or viruses that can unfold finally of the body. Some of us own been hospitalized or died from these infections. Some of us own had severe infections of their lungs while taking OPZELURA. Your healthcare provider ought to glance you carefully for indicators and indicators of TB finally of medication with OPZELURA.

OPZELURA ought to now not be dilapidated in of us with an brisk, severe infection, including localized infections. You mustn’t originate the usage of OPZELURA ought to you own got any more or much less infection unless your healthcare provider tells you it’s okay. You must perchance well presumably be at a increased agonize of growing shingles (herpes zoster) while the usage of OPZELURA.

Elevated agonize of death attributable to any reason (all causes): Elevated agonize of death has took space in of us 50 years of age and older who own as a minimal 1 coronary heart illness (cardiovascular) agonize element and are taking a medication in the category of medicines known as JAK inhibitors by mouth.

Most cancers and immune machine problems: OPZELURA could perchance well merely lift your agonize of distinct cancers by changing the vogue your immune machine works. Lymphoma and other cancers own took space in of us taking a medication in the category of medicines known as JAK inhibitors by mouth. Folks taking JAK inhibitors by mouth own a increased agonize of distinct cancers including lymphoma and lung most cancers, critically if they are a fresh or previous smoker. Some of us own had pores and skin cancers while the usage of OPZELURA. Your healthcare provider will continuously verify your pores and skin finally of your medication with OPZELURA. Limit the volume of time you exhaust in the daylight. Wear protective clothing while it’s probably you’ll perhaps well presumably presumably be in the solar and employ a mammoth-spectrum sunscreen.

Elevated agonize of major cardiovascular occasions: Elevated agonize of major cardiovascular occasions fair like coronary heart attack, stroke, or death own took space in of us 50 years of age and older who own as a minimal 1 coronary heart illness (cardiovascular) agonize element and taking a medication in the category of medicines known as JAK inhibitors by mouth, critically in fresh or previous people who smoke.

Blood clots: Blood clots in the veins of your legs (deep vein thrombosis, DVT) or lungs (pulmonary embolism, PE) can happen in some of us taking OPZELURA. This is in a position to perhaps well presumably be life-threatening. Blood clots in the vein of the legs (deep vein thrombosis, DVT) and lungs (pulmonary embolism, PE) own took space more on the complete in of us which would be 50 years of age and older and with as a minimal 1 coronary heart illness (cardiovascular) agonize element taking a medication in the category of medicines known as JAK inhibitors by mouth.

Low blood cell counts: OPZELURA could perchance well merely trigger low platelet counts (thrombocytopenia), low red blood cell counts (anemia), and low white blood cell counts (neutropenia). If wished, your healthcare provider will produce a blood test to confirm your blood cell counts finally of your medication with OPZELURA and ought to quit your medication if indicators or indicators of low blood cell counts happen.

Ldl cholesterol will increase: Ldl cholesterol lift has took space in of us when ruxolitinib is taken by mouth. Picture your healthcare provider ought to you own got excessive cholesterol or triglycerides.

Ahead of starting up OPZELURA, expose your healthcare provider ought to you:

  • own an infection, are being handled for one, or own had an infection that would not dash away or keeps coming relief
  • own diabetes, persistent lung illness, HIV, or a delicate immune machine
  • own TB or own been in shut contact with someone with TB
  • own had shingles (herpes zoster)
  • own or own had hepatitis B or C
  • stay, own lived in, or own traveled to distinct parts of the country (fair just like the Ohio and Mississippi River valleys and the Southwest) the place there is an increased probability for getting distinct sorts of fungal infections. These infections could perchance well merely happen or turn out to be more severe ought to you employ OPZELURA. Quiz your healthcare provider ought to you produce now not know ought to you own got lived in an home the place these infections are general.
  • judge you own got an infection or own indicators of an infection such as: fever, sweating, or chills, muscle aches, cough or shortness of breath, blood on your phlegm, weight reduction, heat, red, or painful pores and skin or sores to your body, diarrhea or abdominal ache, burning while you urinate or urinating more on the complete than long-established, feeling very tired
  • own ever had any form of most cancers, or are a fresh or previous smoker
  • own had a coronary heart attack, other coronary heart problems, or a stroke
  • own had blood clots in the veins of your legs or lungs in the previous
  • own excessive cholesterol or triglycerides
  • own or own had low white or red blood cell counts
  • are pregnant or idea to turn out to be pregnant. It is now not all the time known if OPZELURA will hurt your unborn toddler. There is a pregnancy publicity registry for individuals who employ OPZELURA finally of pregnancy. The rationale of this registry is to own knowledge concerning the health of you and your toddler. Must you turn out to be exposed to OPZELURA finally of pregnancy, you and your healthcare provider ought to file publicity to Incyte Corporation at 1-855-463-3463.
  • are breastfeeding or idea to breastfeed. It is now not all the time known if OPZELURA passes into your breast milk. Enact now not breastfeed finally of medication with OPZELURA and for roughly 4 weeks after the last dose.

After starting up OPZELURA:

  • Name your healthcare provider true away ought to you own got any indicators of an infection. OPZELURA can own you more inclined to discover infections or own worse any infections that you own got got.
  • Earn emergency succor true away ought to you own got any indicators of a coronary heart attack or stroke while the usage of OPZELURA, including:
    • discomfort in the guts of your chest that lasts for more than a dinky while, or that goes away and springs relief
    • severe tightness, ache, power, or heaviness on your chest, throat, neck, or jaw
    • ache or discomfort on your arms, relief, neck, jaw, or abdominal
    • shortness of breath with or without chest discomfort
    • breaking out in a cool sweat
    • nausea or vomiting
    • feeling lightheaded
    • weak point in a single section or on one aspect of your body
    • slurred speech
  • Picture your healthcare provider true away ought to you own got any indicators and indicators of blood clots finally of medication with OPZELURA, including: swelling, ache, or tenderness in a single or every legs, surprising, unexplained chest or upper relief ache, or shortness of breath or snarl respiratory.
  • Picture your healthcare provider true away ought to you own or own worsening of any indicators of low blood cell counts, fair like: unparalleled bleeding, bruising, tiredness, shortness of breath, or fever.

Picture your healthcare provider about your complete medicines you elevate, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Essentially the most long-established aspect results of OPZELURA in of us handled for atopic dermatitis comprise: general cold (nasopharyngitis), diarrhea, bronchitis, ear infection, lift in a form of white blood cell (eosinophil) depend, hives, infected hair pores (folliculitis), swelling of the tonsils (tonsillitis), and runny nose (rhinorrhea).

Essentially the most long-established aspect results of OPZELURA in of us handled for nonsegmental vitiligo comprise: pimples at the applying space, itching at the applying space, general cold (nasopharyngitis), headache, urinary tract infection, redness at the applying space, and fever.

These are now not the general conceivable aspect results of OPZELURA. Name your physician for clinical advice about aspect results. You must perchance well merely file aspect results to FDA at 1-800-FDA-1088. You must perchance well merely moreover file aspect results to Incyte Corporation at 1-855-463-3463.

INDICATIONS AND USAGE

OPZELURA is a prescription medication dilapidated on the pores and skin (topical) for:

  • brief-term and non-continuous persistent medication of delicate to moderate eczema (atopic dermatitis) in non-immunocompromised adults and younger of us 12 years of age and older whose illness is now not neatly managed with topical prescription therapies or when these therapies are now not instantaneous
  • the medication of a form of vitiligo known as nonsegmental vitiligo in adults and younger of us 12 years of age and older

The usage of OPZELURA alongside with therapeutic biologics, other JAK inhibitors, or solid immunosuppressants fair like azathioprine or cyclosporine is now not instantaneous.

It is now not all the time known if OPZELURA is precise and effective in children much less than 12 years of age with atopic dermatitis or nonsegmental vitiligo.

Please glance the Fat Prescribing Data, including Boxed Warning, and Remedy Data for OPZELURA.

OPZELURA, Incyte, and the Incyte emblem are registered trademarks of Incyte.

© 2024, Incyte Corporation. MAT-OPZ-01931 01/24

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