Dietary vitamin E may be protective against atopic dermatitis

Dietary intake of vitamin E could perhaps doubtlessly lower the possibility for atopic dermatitis, in step with a leer published online Aug. 9 in Pores and skin Review & Skills.

Siqing Wang, from the Beijing University of Chinese Medicine, and colleagues performed a Mendelian randomization diagnosis to acquire the causal relationship between dietary antioxidant vitamin intake (vitamin C, vitamin E, carotene, and retinol) and atopic dermatitis.

The researchers seen a causal relationship between vitamin E intake and atopic dermatitis (odds ratio, 0.859; 95% self perception interval, 0.745 to 0.992; P = 0.038). No causal relationship used to be considered between different three vitamins and atopic dermatitis (odds ratios [95% confidence intervals], 0.953 [0.826 to 1.099; P = 0.507], 1.011 [0.864 to 1.184; P = 0.890], and 1.063 [0.893 to 1.264; P = 0.492] for vitamin C, carotene, and retinol, respectively). In a sensitivity diagnosis, no longer one amongst the single-nucleotide polymorphisms had been detected as heterogeneous and no major pleiotropy used to be seen.

“The diagnosis means that dietary intake of vitamin E could perhaps doubtlessly chop the possibility of atopic dermatitis. Conversely, intake of vitamin C, retinol, and carotene does no longer appear to be causally linked to atopic dermatitis,” the authors write. “Even supposing vitamin E intake could perhaps very well be protective against atopic dermatitis, intake of dietary antioxidant vitamins to forestall or tackle atopic dermatitis is no longer indispensable.”

Extra knowledge:
Siqing Wang et al, Causal relationships between dietary antioxidant vitamin intake and atopic dermatitis: A two‐pattern Mendelian randomization leer, Pores and skin Review and Skills (2024). DOI: 10.1111/srt.13883

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